A landmark controlled trial found that ketamine produced a 64% response rate in treatment-resistant depression within just 24 hours, compared to 28% for the active placebo — a number needed to treat of only 2.8 (Murrough et al., 2013)
Tomball, TX Ketamine Therapy Clinic: Physician-Led Treatment for Depression, Anxiety, PTSD, and Chronic Pain
Rapid-acting ketamine therapy guided by board-certified anesthesiologist Dr. Ho. Three Houston-area locations — all within easy reach of Tomball. Real results for conditions that haven’t responded to traditional treatment. Open 5am–9pm, seven days a week.
Tomball's Closest Ketamine Therapy Clinic
You know the drill by now. A new medication, a cautious dose increase, another round of “let’s see how you feel in six weeks.” Somewhere between prescription number three and prescription number seven, hope starts to feel like a luxury you can’t afford. The medications aren’t failing because you’re doing something wrong — they’re failing because your brain chemistry doesn’t respond to the tools those drugs were designed to use.
Ketamine therapy offers Tomball residents something genuinely different. Instead of adjusting serotonin or dopamine levels and hoping for the best, ketamine activates the glutamate system — your brain’s most expansive communication network — sparking rapid formation of new synaptic connections in areas that depression, anxiety, trauma, and chronic pain have slowly dismantled. For Tomball, TX residents looking for a ketamine therapy clinic backed by real medical expertise, Catalyst Health & Wellness runs three Houston-area locations within a short drive. Dr. Ho brings dual board certifications in anesthesiology and pediatrics — precision you can feel confident in, compassion you’ll notice from your very first interaction.

How Ketamine Therapy Works
Ketamine first appeared in operating rooms in the early 1960s and received FDA clearance as an anesthetic in 1970. Surgeons, emergency physicians, and military medics have trusted it for over fifty years — establishing one of the longest, most thoroughly documented safety records in modern medicine.
Then came the discovery that reshaped psychiatric treatment. In the early 2000s, NIH researchers administered a tiny fraction of the anesthetic dose to patients trapped in severe, treatment-resistant depression. Within hours — not weeks, not months — their symptoms began to lift. According to the Cleveland Clinic, ketamine works by blocking specific glutamate signals in the brain, protecting nerve cells and enabling them to form new, healthy connections through a process called synaptogenesis.
This isn't speculative science. The clinical evidence is substantial:
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How We Administer Ketamine at Catalyst
Our ketamine therapy clinic near Tomball offers two clinically validated delivery methods. Each carries distinct advantages, and your care team will recommend the approach best aligned with your medical history and comfort level.

IV Ketamine Therapy
Intravenous delivery sends ketamine directly into your bloodstream via a small catheter, allowing your medical team to calibrate the infusion rate with pinpoint accuracy throughout the session. If your body needs a slightly higher or lower dose at any point, adjustments happen instantly. Sessions for mood disorders typically last 40 to 60 minutes. IV administration produces the most consistent plasma concentrations, which is why it remains the preferred method among many ketamine specialists.

IM Ketamine Therapy
Intramuscular delivery uses a single injection — usually in the upper arm or thigh — eliminating the need for IV access entirely. The medication absorbs quickly and produces the same core neuroplastic benefits. Patients who dislike needles or who have difficult vein access often prefer this streamlined option. You'll still receive continuous monitoring in a private treatment room, with the same attentive care as an IV session. Both routes deliver strong clinical results. The right choice depends on your individual physiology and preferences — something we'll sort out together during your initial consultation.
Conditions Our Ketamine Therapy Clinic Near Tomball Treats
Ketamine addresses a remarkably wide range of conditions because they all share a common thread: disrupted or degraded neural connections that conventional medications struggle to repair.
Depression Treatment
Relief when years of antidepressants have fallen short
Read MoreAnxiety Treatment
Quieting the constant internal alarm that steals your peace
Read MorePTSD Treatment
Loosening trauma's hold on your nervous system and daily life
Read MoreChronic Pain Treatment
Targeting pain at its central nervous system origin
Read MoreOCD Treatment
Breaking the exhausting cycle of obsessions and compulsions
Read MoreAddiction Treatment
Supporting recovery by reducing cravings at their neurological source
Read MoreBipolar Depression Treatment
Managing depressive episodes with precision and care
Read MoreSuicidality Treatment
Fast-acting intervention when every hour matters
Read MoreFibromyalgia Treatment
Addressing body-wide pain through its neurological roots
Read MoreMigraine Treatment
Disrupting entrenched headache cycles from the inside out
Read MoreEhlers-Danlos Syndrome
Treating the complex, overlapping pain of connective tissue disorders
Read MoreAdolescent Depression
Careful, evidence-based treatment for teens who need more than standard options
Read MoreYour treatment plan won't be pulled from a template. We design every protocol around your specific diagnoses, symptom patterns, and personal goals — then refine it as we learn how you respond.
Your Ketamine Therapy Experience, Step by Step
Every detail of this process was designed to remove uncertainty and keep you feeling supported from your very first phone call to your long-term maintenance plan.
Step 1: Free Phone Consultation
One call gets the conversation started. No forms, no insurance hurdles, no doctor’s referral — just a straightforward discussion with someone who’s heard stories like yours and genuinely wants to help.
Here’s what we’ll cover:
- Where you are right now — your symptoms, your history, what you’ve already tried
- Whether ketamine therapy fits your particular situation
- Exactly what a treatment session looks like from arrival to departure
- Scheduling, cost, and any logistical questions
- Every concern you have, no matter how small it seems
This call is free. It commits you to nothing. It’s simply the information you deserve to make a fully informed decision.
Step 2: Before Your First Visit
Once you decide to move forward, we’ll send you a straightforward medical history form. This goes beyond checking boxes — we want to understand your full picture: what medications you’ve taken, what’s worked even partially, what made things worse, and how your symptoms affect your daily life. If you’re comfortable with it, we’ll also reach out to your current doctor or therapist to coordinate care. None of this is required, but it helps us build a treatment plan that’s tailored to you from day one.
Step 3: Day of Treatment
Getting ready for your appointment is uncomplicated:
- Don’t eat for at least 6 hours beforehand
- Small sips of clear liquids are fine up to 2 hours before
- Dress in whatever feels comfortable and relaxed
When you walk in:
- We’ll answer any last-minute questions still on your mind
- Take your vital signs as a baseline
- Set up your IV (for IV ketamine) or prepare your injection site (for IM)
Dr. Ho selects the smallest gauge IV needles available. His years as a pediatrician made him exceptionally good at gentle needle placement — a skill that adult patients appreciate just as much. If you’re needle-sensitive, we can apply a topical numbing agent beforehand. For patients with difficult veins, Dr. Ho uses ultrasound guidance to get the placement right on the first try.
Step 4: Your Treatment Session
You’ll sink into a padded recliner inside your own private treatment room. We lower the lights and set the atmosphere to whatever helps you feel most at ease.
Everything you need is within reach:
- Noise-cancelling headphones
- Curated playlists of calming music
- A lightproof eye mask
- A warm blanket
- Lighting you can adjust to your preference
How long your session lasts depends on what we’re treating:
- Mood disorders (depression, anxiety, PTSD, OCD): approximately 40 minutes of treatment followed by 20 minutes of recovery
- Chronic pain conditions (fibromyalgia, migraines, EDS, complex pain): approximately 4 hours of treatment followed by 2 hours of recovery
The longer protocol for chronic pain allows us to fully engage the complex central pain pathways involved in conditions like fibromyalgia, migraine headaches, and Ehlers-Danlos Syndrome.
Throughout the entire session, we monitor your blood pressure, heart rate, and oxygen levels at regular intervals. Dr. Ho or a member of our clinical team will either be right there in the room with you or stationed just outside the door, checking in frequently. Feeling nervous before your first treatment is completely normal — nearly everyone does. But by the time that first session wraps up, most patients describe the experience as surprisingly peaceful, safe, and even rejuvenating.
Step 5: Recovery & Aftercare
Once your treatment winds down, you’ll rest in our comfortable recovery space until the effects settle and you feel steady again. Most patients describe a gradual return to clarity over 20 to 60 minutes, depending on the treatment type.
A few important things to keep in mind afterward:
- You absolutely cannot drive yourself home — please arrange your ride before arriving
- Spend the rest of the day with a trusted friend or family member when possible
- Hold off on major decisions, strenuous physical activity, and operating any heavy equipment
- We’ll follow up with a phone call later that day or the next morning to check on you
At the doses we administer at Catalyst Health & Wellness, serious complications are exceptionally rare. Still, our team is always reachable if something feels off or you simply have questions after you leave.
Step 6: Follow-Up & Maintenance
Some patients feel a dramatic shift after a single session. Others build steadily toward their breakthrough over several treatments. Neither response is better or worse — they’re just different roads to the same destination.
Here’s what our typical protocol looks like:
- Initial series: 6 sessions spread across 2 to 3 weeks for mood-related conditions
- Dose fine-tuning between sessions if your response suggests we should adjust
- A personalized maintenance schedule shaped entirely by your results — some patients come back every few weeks, others stretch to monthly visits
- Continuous evaluation at each appointment to make sure your treatment keeps pace with your progress
Because no two patients carry the same history, no two treatment plans should look identical. We monitor, we listen, and we adapt — making sure your ketamine therapy evolves alongside your healing.
The Science Supporting Ketamine Therapy
Ketamine’s reputation as a psychiatric treatment rests on more than anecdotal success stories. It’s backed by rigorous, peer-reviewed research spanning randomized controlled trials, brain imaging studies, and large-scale clinical data.
The study that started it all — conducted at the National Institutes of Health — found a staggering 71% response rate in patients with treatment-resistant depression after a single ketamine infusion. The placebo group? Zero percent. No psychiatric medication in history had ever produced such a dramatic head-to-head contrast (Zarate et al., 2006).
A larger, more rigorously designed multi-site trial followed. Using an active placebo to control for sedation effects, researchers confirmed that ketamine still delivered a 64% response rate within 24 hours — more than double the control group’s 28% — with a number needed to treat of just 2.8 (Murrough et al., 2013).
Neuroscience research published in Science explained why these results happen so fast. Ketamine directly reverses synaptic erosion caused by chronic stress and depression, increasing both the number and signaling strength of neural connections in the prefrontal cortex within a single day (Li et al., 2010).
PTSD research has proven equally compelling. A controlled trial at the Icahn School of Medicine demonstrated that repeated ketamine infusions produced significant, lasting improvement in PTSD symptoms — with approximately two-thirds of participants meeting clinical response criteria (Feder et al., 2014).
Tomball and the surrounding northwest Houston communities aren’t immune to these challenges. The City of Tomball serves a growing population where access to specialized mental health treatment — particularly advanced options like ketamine therapy — has historically required traveling into central Houston. Catalyst’s three Houston-area locations bring that treatment significantly closer to home for Tomball residents.
What the evidence tells us:
- Ketamine operates through the glutamate system — a completely separate biological mechanism from every traditional antidepressant on the market
- Treatment-resistant depression response rates consistently land between 60-71%, far surpassing outcomes from conventional medication switches
- New synaptic connections form within hours, directly observed through neuroimaging — the fastest structural brain change documented for any psychiatric treatment
- The same glutamate-driven mechanism benefits multiple conditions simultaneously: depression, anxiety, PTSD, OCD, chronic pain, and suicidal ideation

Why Tomball Residents Trust Catalyst for Ketamine Therapy
01
Anesthesiology Expertise at the Core
02
Your History Shapes Your Treatment
We don’t believe in one-size-fits-all protocols. Before your first infusion, we map your complete clinical landscape: medications tried and failed, current prescriptions, physical health factors, sleep quality, stress triggers, and what you’re actually hoping treatment will accomplish. That initial picture informs every decision, and we keep refining as new data comes in from each session. Your plan stays as dynamic as your recovery.
03
Convenient Locations Near Tomball
Three Catalyst clinics sit within reasonable driving distance of Tomball, Magnolia, Pinehurst, Spring, and The Woodlands. Regardless of which location works best for your commute, you’ll find the same medical standards, the same comfort-first treatment rooms, and the same dedicated team.
- Catalyst Health & Wellness Heights 104 W. 12th Street, Suite B, Houston, TX 77008
- Catalyst Health & Wellness Southwest 7710 Beechnut, Suite 206, Houston, TX 77074
- Catalyst Health & Wellness South Loop 6300 West Loop S, Suite 526, Bellaire, TX 77401
04
A Full Spectrum of Advanced Treatment Options
Ketamine is our cornerstone, but it’s not our only tool. Catalyst also offers Spravato, TMS therapy, and stellate ganglion block — meaning we can craft multi-modality treatment plans without sending you to separate providers. One team coordinates everything, ensuring each treatment complements the others.
TMS Therapy
Magnetic brain stimulation targeting depression and OCD
Spravato Treatment
FDA-approved esketamine nasal spray with insurance potential
Stellate Ganglion Block
Nerve block procedure for PTSD, anxiety, and pain
Beyond IV and IM ketamine, we offer additional innovative treatments that can complement your ketamine therapy:
05
Every Day, Early Morning to Late Evening
All three locations operate from 5am to 9pm, Monday through Sunday. Whether you need a session before dawn, during a lunch break, after the kids are in bed, or on a Saturday afternoon — we’ve made room for it. Treatment shouldn’t require rearranging your entire life.
Begin Ketamine Therapy Near Tomball, TX Today

Every medication that didn’t work taught your doctors something. Every therapy session that fell short narrowed the search. You haven’t been wasting time — you’ve been eliminating options that weren’t built for your brain chemistry. Ketamine therapy targets the one system those other treatments couldn’t reach.
Your next step takes about ten minutes. Call (713) 772-5315, and we’ll have an honest conversation about your history, your symptoms, and whether ketamine makes sense for you. No cost, no commitment, no sales pitch — just the clarity you need to make your own informed decision.
Monday-Sunday, 6am-9pm
Free consultation
Personalized care
Three Houston locations
Expert medical team
Commonly Asked Questions
Get Help NowHow fast does ketamine start working?
Many patients notice improvements within hours of their first treatment, though some people need a few sessions before experiencing the full benefit. This rapid action is one of ketamine’s most remarkable qualities, especially compared to traditional antidepressants that can take 4 to 8 weeks to work.
Is it safe to undergo ketamine therapy?
Yes, when administered by trained medical professionals in a controlled setting. Ketamine has been used safely as an FDA-approved anesthetic for over 50 years. Dr. Ho’s expertise as an anesthesiologist ensures the highest safety standards. We monitor your vital signs throughout treatment, and serious complications are rare.
What does a full ketamine treatment plan involve?
Most patients receive an initial series of six treatments over two to three weeks. After that, you’ll likely need maintenance treatments to sustain your improvements. The frequency varies based on individual response. Some people return every few weeks, while others maintain their benefits with monthly treatments. We’ll work with you to find the schedule that keeps you feeling your best.
What should I expect to feel during a ketamine session?
Experiences vary from person to person. Many patients describe feeling relaxed, peaceful, or slightly disconnected from their surroundings. Some people have visual or sensory experiences, while others simply feel calm. These effects are temporary and subside as the ketamine wears off. Most patients find the experience pleasant and therapeutic.
Will I need someone to take me home after treatment?
No, you cannot drive yourself home after ketamine treatment. You’ll need to arrange transportation. By the time you leave our facility, you’ll feel much clearer, but for your safety, you should not drive, operate heavy machinery, or make important decisions for the rest of the day.
How long can I expect the benefits to last?
This varies considerably between individuals. Some people maintain their improvement for weeks or even months after their initial series. Others need more frequent maintenance treatments. During your follow-up appointments, we’ll assess how you’re responding and adjust your maintenance schedule accordingly.
Can I stay on my current prescriptions while doing ketamine therapy?
In most cases, yes. Ketamine typically works well alongside other psychiatric medications. However, we’ll review your complete medication list during your consultation to ensure there are no contraindications. Never stop taking prescribed medications without consulting your prescribing physician.
Is a doctor's referral required to get started?
No, you don’t need a referral to begin ketamine therapy at Catalyst Health & Wellness. However, communication with your current healthcare providers can be helpful, and we encourage coordination of care whenever possible.
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