Our Schedule
Adolescent Depression Treatment in Houston: Hope and Healing for Teens
Effective adolescent depression treatment at Catalyst Health & Wellness. Ketamine, TMS, and stellate ganglion block therapy for treatment-resistant teen depression. Three Houston locations. Free consultation.
Watching your teenager struggle with depression is heartbreaking. You’ve noticed the changes: sleeping all day or not at all, withdrawing from friends and activities they used to love, declining grades, irritability, and a sadness that just won’t lift. Maybe they’ve told you they feel hopeless, or that nothing matters anymore. You’ve tried therapy, you’ve tried medications, and yet your teen continues to struggle. You’re worried, exhausted, and desperate to find something that will actually help.
You’re not alone in this frightening journey. Major depression is one of the most prevalent psychiatric disorders in adolescents. An estimated 21 million U.S. adults had at least one major depressive episode in 2021, with the highest prevalence among individuals aged 18 to 25. Depression often starts during the teenage years, affecting roughly 13% of adolescents between ages 12 and 17. For many teens, traditional antidepressants provide incomplete relief or cause intolerable side effects. Worse, the time between medication adjustments means your teen may wait weeks or months to know if a treatment will work.

At Catalyst Health & Wellness, we specialize in innovative adolescent depression treatment for Houston teens who haven’t found adequate relief with traditional approaches. Our treatments work rapidly through different mechanisms than standard antidepressants, offering new hope for teens struggling with treatment-resistant depression. Research shows that ketamine and TMS can provide fast-acting relief for adolescent depression, sometimes within hours or days rather than weeks. With three convenient locations across Houston and extended hours seven days a week, we’re here to help your teen find relief and rediscover hope.
Understanding Adolescent Depression and Treatment-Resistant Depression in Teens
What is Adolescent Depression?
Adolescent depression isn’t just moodiness or typical teenage angst. It’s a serious mental health condition that affects how teens think, feel, and function in their daily lives. Major depressive disorder in adolescents involves persistent feelings of sadness, hopelessness, and loss of interest in activities that lasts for at least two weeks.
Depression in teenagers often looks different than depression in adults. Teens may show persistent sad or irritable mood (irritability is more common in teens than adults), loss of interest in activities they used to enjoy, significant changes in sleep (sleeping all day or insomnia), changes in appetite or weight, fatigue and loss of energy, difficulty concentrating or making decisions, feelings of worthlessness or excessive guilt, physical complaints like headaches or stomachaches, social withdrawal from friends and family, and declining academic performance.
For some teens, depression also involves thoughts of death or suicide. Suicide is the second leading cause of death among adolescents and young adults. Up to 80% of adolescents who attempt suicide meet the criteria for depression at the time of the attempt. This is why rapid, effective treatment is so critically important.
The experience of depression during the teenage years can be particularly devastating. These are formative years for developing identity, relationships, and future direction. Depression can derail academic achievement, damage social connections, and create patterns of negative thinking that persist into adulthood. Teens with depression also face higher risk of substance use, self-harm, and other risky behaviors.
How Depression Develops in Teens
Depression in adolescents develops from a combination of biological, psychological, and environmental factors. Genetics play a significant role, with teens who have a family history of depression at higher risk. Brain chemistry differences, particularly involving neurotransmitters like serotonin and norepinephrine, contribute to depression. Hormonal changes during puberty can trigger or worsen depressive symptoms.
Environmental stressors also matter tremendously. Trauma, bullying, academic pressure, social isolation, family conflict, and loss can all trigger depression in vulnerable teens. The pressure of social media and constant comparison to peers creates additional stress that previous generations didn’t face.
Some teens are at higher risk for depression. Girls are twice as likely as boys to experience depression during adolescence. LGBTQ+ youth face significantly elevated rates of depression compared to their heterosexual peers. Teens with learning disabilities, chronic medical conditions, or other mental health conditions like anxiety or ADHD also have higher depression rates.
Treatment-Resistant Depression in Adolescents
When a teenager tries standard depression treatments without achieving adequate relief, they may have treatment-resistant depression. Traditional treatment typically involves psychotherapy (cognitive behavioral therapy or interpersonal therapy), antidepressant medications (usually SSRIs like fluoxetine or escitalopram), lifestyle changes (exercise, sleep hygiene, stress management), and family involvement and support.
While these approaches help many teens, a significant percentage continues experiencing severe depression despite treatment. The FDA has approved only a few antidepressants specifically for adolescents, and these medications work for only about 60% of teens who try them. Even when antidepressants work, they typically take 4 to 6 weeks to show effects, which feels like an eternity when your teen is suffering.
Some teens can’t tolerate the side effects of antidepressants, which can include weight gain, sexual dysfunction, emotional numbness, or increased anxiety. Others improve slightly but don’t achieve full remission of symptoms. Some stop responding to medications that initially helped.
The reasons for treatment resistance in teens vary. Some adolescents have particularly severe depression that doesn’t respond to first-line treatments. Others have co-occurring conditions like trauma, anxiety, or substance use that complicate treatment. Some teens struggle with medication adherence or find therapy difficult.
The frustration and fear of watching your teen struggle despite treatment can be overwhelming. Many parents tell us they felt helpless as their child continued to suffer. We want you to know that innovative treatments are available that work through entirely different mechanisms than what your teen has tried before, and they often work much faster.
Innovative Adolescent Depression Treatments at Catalyst Health & Wellness
We offer three advanced treatment options specifically for adolescent depression. Each works through unique mechanisms to provide rapid relief from depressive symptoms. IMPORTANT: We only treat adolescents ages 13-17. Parental consent and involvement is required for all minor patients.
Ketamine Therapy for Adolescent Depression in Houston
Research shows ketamine can provide rapid relief for adolescent treatment-resistant depression. A randomized, controlled trial found that 76% of adolescents with major depression responded to a single ketamine infusion compared to 35% who received a control medication. Another study showed repeated ketamine infusions rapidly improved depressive symptoms in adolescents at imminent risk for suicide. Ketamine works through the glutamate system rather than serotonin, offering an entirely different approach. Effects can begin within hours rather than weeks. We offer both IV and IM ketamine specifically for teens ages 13-17 with parental consent.
Learn more about Ketamine TherapyTMS Therapy for Adolescent Depression
Transcranial Magnetic Stimulation (TMS) is FDA-cleared for adolescents with treatment-resistant depression. TMS uses magnetic pulses to stimulate brain regions involved in mood regulation. The treatment is non-invasive, produces no systemic side effects, and doesn't require any medications. Research demonstrates TMS effectively reduces depression in teens who haven't responded to antidepressants. Daily sessions over several weeks can provide significant and lasting symptom relief. TMS is particularly appropriate for teens and parents concerned about medication side effects.
Learn more about TMS TherapyStellate Ganglion Block for Adolescent Depression
Stellate ganglion block (SGB) can help with adolescent depression, particularly when depression occurs alongside significant anxiety, trauma symptoms, or stress response dysregulation. The procedure reduces sympathetic nervous system overactivity and may help regulate mood. SGB is a quick procedure that some adolescents respond to dramatically. It may be particularly helpful for teens whose depression started after trauma or who experience significant anxiety alongside depression.
Learn more about Stellate Ganglion BlockWhat to Expect During Adolescent Depression Treatment at Catalyst
Your First Step: Comprehensive Assessment with Parent and Teen
Treatment for adolescent depression begins with a thorough assessment involving both the teen and parent(s). We need to understand your teen’s unique experience to develop the most effective treatment plan.
During your consultation, we’ll discuss:
- Your teen’s depression history and symptoms
- Previous treatments tried and their effectiveness
- Current medications and therapy
- School performance and social functioning
- Family history of mental health conditions
- Any suicidal thoughts or self-harm behaviors
- Co-occurring conditions like anxiety or trauma
- Your teen’s goals and what matters most to them
- Which innovative treatments might work for your teen’s situation
IMPORTANT: For all adolescent patients (ages 13-17), parental consent is required, and parents are involved in the treatment planning process. However, we also speak with teens individually to understand their perspective and ensure they feel heard.
There’s no obligation to continue, and everything we discuss remains confidential (with appropriate exceptions for safety concerns). We understand how frightening it is to watch your teen struggle, and we approach these conversations with expertise, empathy, and without judgment.
Creating Your Teen's Personalized Treatment Plan
If you and your teen decide to proceed, we’ll develop a comprehensive treatment plan designed specifically for your adolescent.
Your teen’s personalized plan considers:
- Severity of depression and any suicidal ideation
- Previous treatment responses
- Co-occurring conditions (anxiety, trauma, ADHD)
- Medication sensitivities or side effects experienced
- Your teen’s and family’s treatment preferences
- School and activity schedules
- Need for rapid intervention vs. gradual improvement
- How to integrate our treatments with ongoing therapy
Your teen continues their current treatments (therapy and medications) while receiving ketamine, TMS, or SGB. We don’t replace your teen’s psychiatrist or therapist. Instead, we add innovative treatments that work through different mechanisms to enhance overall outcomes. We coordinate closely with your teen’s existing providers to ensure comprehensive care.
Some teens benefit most from a series of ketamine infusions or TMS sessions for breakthrough symptom relief. Others use these treatments as part of ongoing depression management alongside medications and therapy. We tailor the approach to your teen’s specific needs and safety.
During Your Teen's Treatment
Every treatment session takes place in a comfortable, supervised environment with continuous medical monitoring. Parents are welcome and encouraged to be present during all treatment sessions for adolescent patients.
What makes adolescent treatment at Catalyst different:
- Specialized experience treating teens ages 13-17
- Required parental involvement and consent
- Comfortable environment appropriate for young people
- Extended hours: 5am to 9pm, seven days a week
- Flexible scheduling around school and activities
- Led by Dr. Ho, anesthesiologist and former pediatrician
- Continuous monitoring throughout treatment
- Understanding of adolescent development and needs
- Coordination with existing mental health providers
- Compassionate, teen-friendly care
Dr. Ho’s background includes both anesthesiology and pediatrics, giving him unique expertise in treating younger patients safely. Whether your teen receives ketamine, TMS, or stellate ganglion block, our medical team monitors them carefully throughout the session.
We understand that teens are not just small adults. They’re going through unique developmental stages, facing age-specific stressors, and need treatment approaches that acknowledge their specific needs. Our entire team approaches adolescent care with appropriate expertise and sensitivity.
Following Your Teen's Initial Treatment Series
Typical treatment protocols for adolescent depression:
- Ketamine: 6 infusions over 2-3 weeks initially, then maintenance as needed
- TMS: Daily sessions (weekdays) over 4-6 weeks
- Stellate Ganglion Block: 1-3 treatments
- Maintenance: Periodic booster treatments to maintain symptom relief
After your teen’s initial treatment series, we develop a maintenance plan in coordination with their psychiatrist and therapist. Many teens need periodic booster treatments to maintain improvement. Some continue regular maintenance ketamine infusions or TMS sessions every few weeks or months. Others use our treatments as a bridge until they find the right medication combination.
We’re committed to your teen’s long-term mental health. Regular follow-up appointments help us monitor symptoms, adjust treatment as needed, coordinate with other providers, and support your teen’s ongoing recovery and development.
The Science Behind Our Adolescent Depression Treatments
Understanding why these treatments work helps both parents and teens feel more confident about trying them. Traditional antidepressants work by increasing serotonin or norepinephrine in the brain. While these medications help many people, they take weeks to work and don’t help everyone.
Ketamine works through an entirely different mechanism. It affects the glutamate system, the brain’s most abundant neurotransmitter. Ketamine blocks NMDA receptors, which triggers a cascade of events that rapidly promote neuroplasticity. Essentially, ketamine helps the brain form new connections and pathways, allowing it to break free from depressive patterns.
How ketamine works for adolescent depression:
- Works through glutamate system, not serotonin
- Promotes rapid neuroplasticity and new neural connections
- Effects can begin within hours, not weeks
- Reduces depressive symptoms and suicidal thoughts quickly
- May help the brain respond better to therapy and other treatments
- Creates a window of opportunity for psychological healing
Research on ketamine for adolescent depression:
- A randomized trial showed 76% of teens responded to ketamine vs. 35% to control
- Studies show rapid reduction in suicidal ideation in adolescents
- Research demonstrates ketamine is well-tolerated in teens
- Effects on the adolescent brain are being carefully studied
- Used cautiously with appropriate monitoring and parental involvement
How TMS works for adolescent depression:
- Uses magnetic pulses to stimulate underactive brain regions
- Targets the prefrontal cortex involved in mood regulation
- FDA-cleared specifically for adolescent treatment-resistant depression
- Non-invasive with no systemic medications
- Daily treatments gradually improve mood and functioning
- Effects build over several weeks and can be long-lasting
How stellate ganglion block works for adolescent depression:
- Reduces sympathetic nervous system overactivity
- Helps regulate the stress response system
- May be particularly effective for depression with anxiety or trauma
- Quick procedure with potential for rapid symptom improvement
- Can help reset dysregulated stress responses
Important considerations for adolescent treatment:
- The teenage brain is still developing, particularly the prefrontal cortex
- Treatments are used cautiously with appropriate monitoring
- Parental involvement and consent are required
- Close coordination with existing mental health providers is essential
- Long-term effects continue to be studied carefully
These aren’t experimental treatments. They’re supported by growing research specifically in adolescent populations and continue to demonstrate safety and effectiveness for teens who haven’t found adequate relief with traditional approaches.
Three Convenient Houston Locations
Catalyst Health & Wellness Heights
104 W. 12th Street, Suite B, Houston, TX 77008
(713) 772-5315Serving Heights, Montrose, Garden Oaks, and Greater Houston
Catalyst Health & Wellness Southwest
7710 Beechnut, Suite 206, Houston, TX 77074
(713) 772-5315Serving Southwest Houston, Bellaire, Meyerland, and Greater Houston
Catalyst Health & Wellness South Loop
6300 West Loop S, Suite 526, Houston, TX 77401
(713) 772-5315Serving Galleria, Medical Center, West University, and Greater Houston
All Locations Open: Monday-Sunday, 5am-9pm
Why Choose Catalyst Health & Wellness for Adolescent Depression Treatment in Houston
Specialized Experience with Teens
We have specific experience treating adolescents ages 13 to 17 with depression. We understand the unique needs of this age group and the importance of developmentally appropriate care. Dr. Ho’s background includes pediatrics, giving him specialized expertise in treating younger patients.
Required Parental Involvement
We recognize that treating adolescent depression requires family involvement. Parents are required to provide consent and are encouraged to be present during all treatment sessions. We coordinate closely with parents and existing providers to ensure comprehensive, safe care.
Rapid Symptom Relief
When your teen is suffering, every day matters. Unlike traditional antidepressants that take 4 to 6 weeks to work, ketamine can provide relief within hours or days. TMS begins to show effects within a few weeks. This rapid relief can be life-changing for teens in crisis or experiencing severe depression.
Coordination with Existing Care
We work closely with your teen’s psychiatrist, therapist, and other mental health providers. Our treatments complement rather than replace existing care. We provide detailed updates to other providers (with your consent) to ensure everyone is working together toward your teen’s recovery.
Understanding Adolescent Development
We recognize that teens are not just small adults. They’re navigating unique developmental challenges, peer relationships, academic pressures, and identity formation. Our approach acknowledges these factors and treats your teen with age-appropriate understanding and respect.
Addressing Co-Occurring Conditions
Many teens with depression also struggle with anxiety, PTSD, ADHD, or other conditions. We can address these co-occurring issues as part of comprehensive treatment, since improving one condition often helps others.
Signs Your Teen May Benefit from Our Adolescent Depression Treatment
Consider reaching out to Catalyst Health & Wellness if your teen:
- Has tried at least two antidepressants without adequate relief
- Can’t tolerate side effects of antidepressant medications
- Experiences severe depression that impacts school, relationships, or functioning
- Has thoughts of suicide or self-harm (seek emergency care if imminent risk)
- Shows no improvement after several months of therapy and medication
- Experiences depression with significant anxiety or trauma symptoms
- Needs rapid relief due to crisis or severe symptoms
- Struggles with medication adherence or doesn’t want long-term medications
- Has depression that started after trauma or a specific event
- Continues to suffer despite everyone’s best efforts
Your teen deserves relief. New treatment options offer hope even when traditional approaches haven’t worked.
Frequently Asked Questions
Is ketamine safe for teenagers?
Research shows ketamine can be safely administered to adolescents with appropriate medical supervision. Studies specifically examining ketamine in teens with depression demonstrate good tolerability. However, ketamine is used cautiously in adolescents because the brain is still developing. We require parental consent, provide continuous medical monitoring, and coordinate closely with your teen’s other providers. The treatment is administered in a controlled medical setting, not self-administered.
Will my child become addicted to ketamine?
When administered in a medical setting for depression treatment, the risk of addiction is very low. We use sub-anesthetic doses in a supervised environment, which is very different from recreational ketamine use. Your teen receives treatment at our facility under medical supervision and doesn’t take ketamine home. We carefully screen for any substance use concerns and monitor closely throughout treatment.
How quickly will my teen feel better?
Many teens experience some improvement within hours or days of their first ketamine treatment, though the full effects develop over a series of treatments. TMS typically shows effects within 2 to 3 weeks of daily sessions. The rapid relief with ketamine can be particularly important for teens experiencing severe depression or suicidal thoughts.
Can my teen stop their antidepressants?
No, your teen should continue their current medications unless their prescribing psychiatrist makes changes. Ketamine and TMS work best as additions to existing treatment, not replacements. Any medication changes should be made gradually under the supervision of your teen’s psychiatrist.
Will insurance cover treatment for my teenager?
TMS for adolescent treatment-resistant depression is often covered by insurance when FDA-cleared devices are used and prior authorization is obtained. Ketamine for depression is typically not covered by insurance as this is an off-label use. We can discuss costs and payment options during your consultation and provide documentation for possible insurance reimbursement.
Do I need to be present during treatment?
We strongly encourage parents to be present during treatment sessions for adolescent patients. You’re welcome to stay with your teen throughout the entire session or wait in our comfortable waiting area. Your presence helps your teen feel more secure and allows you to observe their response to treatment.
What if my teen has suicidal thoughts?
If your teen is currently experiencing suicidal thoughts, this is important information to share during the consultation. Research shows ketamine can rapidly reduce suicidal ideation, sometimes within hours. However, if your teen is in immediate crisis or has a plan to harm themselves, please seek emergency care immediately by calling 988 (Suicide and Crisis Lifeline) or going to the nearest emergency room. We can provide treatment for teens experiencing suicidal thoughts when they’re stable enough for outpatient care.
How does this affect my teen's developing brain?
This is an important question that researchers are studying carefully. Current evidence suggests ketamine used at medical doses under proper supervision doesn’t cause harm to the adolescent brain, but long-term studies continue. The potential benefits of treating severe, treatment-resistant depression must be weighed against theoretical concerns, as untreated depression also significantly impacts adolescent brain development. We discuss these considerations thoroughly with families and use these treatments cautiously with appropriate monitoring.
Adolescent Depression Statistics and Research
Major depression is one of the most prevalent psychiatric disorders in adolescents. Depression often starts during the teenage years, with roughly 13% of adolescents between ages 12 and 17 experiencing at least one major depressive episode. The prevalence is highest among individuals aged 18 to 25 (18.6% in 2021).
The scope of adolescent depression:
- Approximately 13% of adolescents aged 12-17 experience major depression
- Prevalence is higher in teenage girls than boys
- Depression is most commonly associated with suicide in adolescents
- Up to 80% of adolescents who attempt suicide have depression
- Suicide is the second leading cause of death among adolescents and young adults
- Anxiety disorders affect 31.9% of adolescents and often co-occur with depression
- Many teens with depression don’t receive adequate treatment
Despite being so common, adolescent depression remains undertreated. Many teens don’t receive any mental health treatment. Among those who do, traditional antidepressants work for only about 60% of adolescents. The FDA has approved only a few antidepressants specifically for teens. Houston teens face the same challenges as the broader population, with limited access to innovative depression treatments beyond traditional therapy and medications.
Recent research brings new hope for adolescent depression. Research published in the American Journal of Psychiatry demonstrated that ketamine effectively treats adolescent treatment-resistant depression. Studies show ketamine can rapidly reduce suicidal ideation in teens at imminent risk. TMS is FDA-cleared specifically for adolescent treatment-resistant depression based on clinical trial evidence.
The growing body of evidence supporting these innovative treatments means more options are available now than ever before for teens struggling with depression that hasn’t responded to traditional approaches.
Getting Started with Adolescent Depression Treatment in Houston
Watching your teenager struggle with depression is one of the most difficult experiences a parent can face. You’ve tried everything recommended by doctors and therapists. You’ve adjusted medications, attended family therapy, tried to be patient when your teen pushes you away. Yet your child continues to suffer, and you feel helpless. We want you to know that your teen’s struggle is real, and innovative treatments are available that work differently than what you’ve tried before.
Taking the first step toward trying something new requires courage for both you and your teen, especially when you’ve been disappointed by previous treatments. We make that first step as easy as possible. Call us at (713) 772-5315 for a free consultation. During this conversation, you’ll speak with someone who understands adolescent depression and can explain your options clearly.
We have three convenient locations across Houston: in the Heights, Southwest Houston, and near the South Loop. Whichever is most accessible for your family, we’re open from 5am to 9pm every single day to accommodate school and family schedules. Dr. Ho and our entire team are committed to helping your teen find relief and rediscover hope for the future.
Your teen deserves to experience the joy and possibilities of adolescence, not be crushed by depression. You deserve to see your child smile again, engage with life, and look forward to the future. Let us show you what’s possible with innovative adolescent depression treatments.
IMPORTANT: We treat adolescents ages 13-17 with parental consent. If your teen is experiencing a mental health emergency or expressing intent to harm themselves, please call 988 (Suicide and Crisis Lifeline) or go to the nearest emergency room immediately.
Monday-Sunday, 5am-9pm
Ready to Experience Real Relief?
Our compassionate team is here to answer your questions and guide you toward lasting relief. Schedule your consultation today and take the first step toward reclaiming your life.
Book AppointmentBlog & insight
Insights on Healing, Growth, and Mental Wellness

FAQ: Common Questions About Ketamine Treatment Answered
If you've been researching ketamine therapy in Houston, chances are you've come across a lot of conflicting information. One article calls it a miracle cure. Another paints it as a risky party drug. Somewhere in between sits the truth, and you deserve straightforward answers before making any decision about your mental health or chronic pain…

Can Ketamine Therapy Help with Both Depression and Anxiety?
If you've spent years battling depression only to find anxiety creeping in alongside it (or vice versa), you're not imagining the connection. These two conditions show up together far more often than people realize, and the overlap can make recovery feel like trying to untangle a knot that keeps tightening. Traditional antidepressants and anti-anxiety medications…

Neuropathic Pain and Ketamine: Relief When Nerve Pain Won’t Quit
If you live with neuropathic pain, you already know it doesn't behave like ordinary pain. It burns when nothing touched you. It shocks down your leg while you're sitting still. It turns the brush of a bedsheet into something sharp. And the medications your doctor prescribed, the gabapentin, the duloxetine, maybe even opioids, take the…
Make an Appointment
Our mission is to empower individuals to overcome life’s challenges through professional psychological support.
