Approximately 70% of patients with treatment-resistant depression respond to ketamine therapy
Ketamine Therapy in Houston: Fast-Acting Relief for Treatment-Resistant Conditions
Experience breakthrough treatment for depression, anxiety, PTSD, chronic pain, and more at Catalyst Health & Wellness. Led by Dr. Ho, anesthesiologist and former pediatrician. Three convenient Houston locations open 6am-9pm, seven days a week.
Find Lasting Relief with Ketamine Therapy
If you’ve tried multiple medications and therapies without finding relief, you’re not alone. Millions of Americans struggle with treatment-resistant mental health conditions and chronic pain that don’t respond to conventional approaches. Ketamine therapy offers a different path forward, one that works through unique mechanisms in your brain to provide rapid relief when other treatments have failed.
At Catalyst Health & Wellness, we’ve helped countless Houston residents break free from the grip of depression, anxiety, PTSD, and debilitating pain. Our ketamine therapy combines expert medical care with a whole-person approach that considers your mind, body, and spirit. With three locations across Houston and hours that fit your schedule, we’re here to help you reclaim your life.

What is Ketamine Therapy?
Ketamine has been used safely as an FDA-approved anesthetic for over 50 years. More recently, researchers discovered something remarkable: at lower doses, ketamine rapidly alleviates symptoms of depression, anxiety, PTSD, and chronic pain, often within hours of the first treatment.
Unlike traditional antidepressants that work on serotonin, norepinephrine, or dopamine, ketamine targets the glutamate system in your brain. It acts on NMDA receptors to promote neuroplasticity, your brain’s ability to form new neural connections. Think of it as helping your brain “rewire” itself, breaking free from the stuck patterns that keep you trapped in depression, anxiety, or pain.
This mechanism explains why ketamine works so differently than conventional treatments. While traditional antidepressants can take weeks or months to show results (if they work at all), many patients experience noticeable improvement within hours or days of their first ketamine session. For those who’ve waited years for relief, this rapid action can be life-changing.
Research consistently shows powerful results:
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Ketamine Administration Methods at Catalyst
We offer two proven methods of ketamine administration, allowing us to personalize your treatment based on your specific needs and preferences.

IV Ketamine Therapy Houston
IV ketamine delivers medication directly into your bloodstream for rapid, precise relief from depression, anxiety, and chronic pain. This method allows our medical team to adjust your dose in real-time, ensuring optimal results during each 40-60 minute session.

IM Ketamine Therapy Houston
IM ketamine is administered through a quick intramuscular injection, offering the same powerful benefits as IV therapy with a simpler, faster setup. Many patients prefer this option for its comfort and convenience while still experiencing significant relief within hours.
Conditions We Treat with Ketamine Therapy in Houston
Ketamine therapy has shown remarkable effectiveness across a wide range of mental health conditions and chronic pain disorders. At Catalyst Health & Wellness, we specialize in treating:
Depression Treatment
Rapid relief for treatment-resistant depression
Read MoreAnxiety Treatment
Breaking the cycle of persistent worry and fear
Read MorePTSD Treatment
Processing trauma with reduced emotional distress
Read MoreChronic Pain Treatment
Addressing persistent pain conditions
Read MoreOCD Treatment
Disrupting obsessive thought patterns
Read MoreAddiction Treatment
Reducing cravings and supporting recovery
Read MoreBipolar Depression Treatment
Managing depressive episodes safely
Read MoreSuicidality Treatment
Rapid intervention for crisis situations
Read MoreFibromyalgia Treatment
Relief from chronic widespread pain
Read MoreMigraine Treatment
Breaking the cycle of debilitating headaches
Read MoreEhlers-Danlos Syndrome
Managing EDS-related pain and symptoms
Read MoreAdolescent Depression
Safe treatment for teens struggling with depression
Read MoreEach condition responds to ketamine through similar mechanisms: promoting neuroplasticity, reducing inflammation in the brain, and helping reset dysfunctional neural pathways. Your personalized treatment plan will be tailored to address your specific symptoms and goals.
Your Ketamine Therapy Journey at Catalyst Health & Wellness
We've designed every step of your experience to be comfortable, supportive, and focused on your unique needs. Here's what you can expect when you choose Catalyst for ketamine therapy in Houston.
Step 1: Free Phone Consultation
Your journey begins with a no-cost, confidential phone consultation. This isn’t a sales pitch but a genuine conversation where we explore whether ketamine therapy is right for you.
During your consultation, you’ll:
- Ask all your questions about ketamine therapy
- Share your treatment history and current challenges
- Learn what ketamine therapy involves
- Get to know our team in a pressure-free environment
- Receive honest guidance on whether this treatment fits your needs
There’s absolutely no charge and no obligation to continue.
Step 2: Before Your First Visit
If you decide to move forward, we’ll ask you to complete a medical history form. We want to understand you as a whole person: mind, body, and spirit. Communication with your current healthcare provider can be helpful, though it’s not always required. This preparation helps us personalize your treatment from the very start.
Step 3: Day of Treatment
Preparation is simple:
- Avoid eating for 6 hours before your appointment
- Only small amounts of clear liquids 2 hours before
- Wear loose, comfortable clothing
When you arrive:
- We’ll review any last-minute questions
- Check your vital signs
- Start your IV with expert care from Dr. Ho
Dr. Ho uses the smallest IVs possible, and as an anesthesiologist and former pediatrician, he’s highly skilled at making IV placement comfortable. We can apply numbing medication if you’d like, and we have ultrasound equipment available to minimize attempts if needed.
Step 4: Your Treatment Session
You’ll settle into a soft, reclinable chair in our private treatment room. We dim the lights and create a calm, peaceful environment.
Your comfort matters:
- Noise-cancelling headphones available
- Relaxing music
- Lightproof eye mask
- Warm blanket
- Adjustable lighting
Treatment duration:
- Mood disorders: 40 minutes treatment + 20 minutes recovery
- Chronic pain: 4 hours treatment + 2 hours recovery
The extended protocol for chronic pain allows us to address the complex pain pathways involved in conditions like fibromyalgia, migraines, and Ehlers-Danlos Syndrome.
Throughout your session, we’ll monitor your vital signs at regular intervals. Either Dr. Ho or another member of our medical team will be in the room with you or right outside the door, checking on you frequently. Many patients feel anxious before their first treatment, which is completely normal. However, by the end of that first session, most people find the experience safe, relaxing, and even rejuvenating.
Step 5: Recovery & Aftercare
After your treatment ends, you’ll rest in our comfortable recovery area until your head is clear and you feel close to your normal self.
Important aftercare instructions:
- You cannot drive yourself home (arrange transportation in advance)
- Stay in the company of a responsible adult when possible
- Avoid important decisions, vigorous activity, or operating heavy machinery
- We’ll call you later to make sure everything is going well. In the doses we administer at Catalyst Health & Wellness, serious complications are rare. However, we’re always available if you have questions or concerns.
Step 6: Follow-Up & Maintenance
Some people respond remarkably to ketamine therapy after just one treatment. For others, it takes several sessions to achieve the full benefit.
Our typical protocol:
- Initial series: 6 sessions over 2-3 weeks for mood disorders
- Dose adjustments if needed for optimal response
- Personalized maintenance schedule based on your results
- Some patients need treatments every few weeks, others monthly
- Continuous monitoring and adjustment to match your needs
Since everyone’s condition is unique, everyone’s treatment requirements will be different as well. We personalize your care to make sure your treatments match your needs perfectly.
The Science Behind Ketamine for Mental Health
Research published in the journal Science demonstrated that ketamine rapidly reverses the synaptic deficits caused by chronic stress. In animal models, a single dose of ketamine increased the number and function of synaptic connections in the prefrontal cortex (a brain region critical for mood regulation) within just 24 hours.
For PTSD specifically, studies from Yale and Mount Sinai have shown that ketamine reduces symptoms by modifying how the brain processes traumatic memories. It appears to help “reconsolidate” fear memories, making them less emotionally overwhelming. A randomized controlled trial found that 67% of PTSD patients who received repeated ketamine infusions experienced significant improvement in their symptoms.
Key research findings:
- Ketamine promotes rapid synapse formation in mood-regulating brain regions
- Effects often begin within hours, not weeks like traditional antidepressants
- Helps “rewire” dysfunctional neural pathways in depression, anxiety, and PTSD
- May represent the most important breakthrough in antidepressant treatment in decades

Why Choose Catalyst Health & Wellness for Ketamine Therapy
01
Led by Dr. Ho – Expert Medical Care
02
Whole-Person Approach
We don’t just treat symptoms. We treat people. From your very first phone call, we focus on understanding you as a complete person: mind, body, and spirit.
What this means for you:
- Treatment plans personalized to your unique history
- Consideration of your current symptoms and individual goals
- Ongoing adjustments based on what works best for you
- Care that evolves as you progress through treatment
03
Extended Hours & Flexible Scheduling
Life doesn’t stop for treatment, which is why we’re open from 5am to 9pm, seven days a week. Whether you need an early morning appointment before work, an evening session after your responsibilities are done, or weekend treatment, we can accommodate your schedule. All three of our Houston locations offer these extended hours.
04
Comprehensive Treatment Options
Beyond IV and IM ketamine, we offer additional innovative treatments that can complement your ketamine therapy:
TMS Therapy
Non-invasive brain stimulation for depression
Spravato Treatment
FDA-approved nasal esketamine therapy
Stellate Ganglion Block
Targeted treatment for PTSD and pain
Beyond IV and IM ketamine, we offer additional innovative treatments that can complement your ketamine therapy:
05
Safe, Comfortable Environment
Every detail of our treatment rooms has been designed with your comfort in mind. You’ll relax in a soft, reclinable chair in a private room with adjustable lighting. We provide noise-cancelling headphones, calming music, eye masks, and warm blankets. Our medical team is always nearby, usually in the room with you or just outside the door, monitoring your vital signs and ensuring your safety throughout the entire experience.
Getting Started with Ketamine Therapy in Houston

You’ve spent too long struggling with symptoms that won’t respond to conventional treatments. Ketamine therapy offers a proven path forward, one backed by decades of research and real results for people just like you.
Taking the first step is simple. Call us at (713) 772-5315 for your free, no-obligation phone consultation. During this conversation, we’ll answer all your questions, discuss your treatment history, and help you understand whether ketamine therapy is right for you. There’s no pressure, no charge, and everything remains completely confidential.
With three convenient locations across Houston and hours from 6am to 9pm every day of the week, we make it easy to get the care you need when you need it. Dr. Ho and our entire team are here to support you through every step of your healing journey.
Monday-Sunday, 6am-9pm
Free consultation
Personalized care
Three Houston locations
Expert medical team
Commonly Asked Questions
Get Help NowHow quickly does ketamine therapy work?
Many patients notice improvements within hours of their first treatment, though some people need a few sessions before experiencing the full benefit. This rapid action is one of ketamine’s most remarkable qualities, especially compared to traditional antidepressants that can take 4 to 8 weeks to work.
Is ketamine therapy safe?
Yes, when administered by trained medical professionals in a controlled setting. Ketamine has been used safely as an FDA-approved anesthetic for over 50 years. Dr. Ho’s expertise as an anesthesiologist ensures the highest safety standards. We monitor your vital signs throughout treatment, and serious complications are rare.
How many treatments will I need?
Most patients receive an initial series of six treatments over two to three weeks. After that, you’ll likely need maintenance treatments to sustain your improvements. The frequency varies based on individual response. Some people return every few weeks, while others maintain their benefits with monthly treatments. We’ll work with you to find the schedule that keeps you feeling your best.
What does ketamine therapy feel like?
Experiences vary from person to person. Many patients describe feeling relaxed, peaceful, or slightly disconnected from their surroundings. Some people have visual or sensory experiences, while others simply feel calm. These effects are temporary and subside as the ketamine wears off. Most patients find the experience pleasant and therapeutic.
Can I drive after a ketamine session?
No, you cannot drive yourself home after ketamine treatment. You’ll need to arrange transportation. By the time you leave our facility, you’ll feel much clearer, but for your safety, you should not drive, operate heavy machinery, or make important decisions for the rest of the day.
How long do the effects last?
This varies considerably between individuals. Some people maintain their improvement for weeks or even months after their initial series. Others need more frequent maintenance treatments. During your follow-up appointments, we’ll assess how you’re responding and adjust your maintenance schedule accordingly.
Can I continue my current medications?
In most cases, yes. Ketamine typically works well alongside other psychiatric medications. However, we’ll review your complete medication list during your consultation to ensure there are no contraindications. Never stop taking prescribed medications without consulting your prescribing physician.
Do I need a referral from my doctor?
No, you don’t need a referral to begin ketamine therapy at Catalyst Health & Wellness. However, communication with your current healthcare providers can be helpful, and we encourage coordination of care whenever possible.
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